Big data is changing how research is being conducted and allowing new kinds of questions to be asked. Meanwhile, data management has enabled a rapid increase in the dissemination and preservation of research products and many funding agencies like the National Science Foundation and National Institute of Health now require data management plans in their grant applications. The combination of big data applications and data management processes has created new opportunities and pitfalls for researchers. In the past year, prominent scientists including the Director of the NIH have suggested that inappropriate methodology for data acquisition, analysis and storage has led to a gap in the translation of basic research findings to clinical cures. In this session we will track data through all research stages, describe best practices and university resources available to faculty grappling with these important issues.